Peer reviewed articles

• Sharabi, K., Hurwitz, A., Simon, A.J., Beitel, G.J., Morimoto, R.I., Rechavi, G., Sznajder, J.I., and Gruenbaum, Y. (2009a). Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans. Proc Natl Acad Sci U S A 106, 4024-4029.
• Vadasz, I., Dada, L.A., Briva, A., Helenius, I.T., Sharabi, K., Welch, L.C., Kelly, A.M., Grzesik, B.A., Budinger, G.R., Liu, J., et al. (2012). Evolutionary conserved role of c-Jun-N-terminal kinase in CO2-induced epithelial dysfunction. PLoS One 7, e46696.
• Barkan, R., Zahand, A.J., Sharabi, K., Lamm, A.T., Feinstein, N., Haithcock, E., Wilson, K.L., Liu, J., and Gruenbaum, Y. (2012). Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis. Mol Biol Cell 23, 543-552.
• Sharabi, K., Charar, C., Friedman, N., Mizrahi, I., Zaslaver, A., Sznajder, J.I., and Gruenbaum, Y. (2014). The response to high CO2 levels requires the neuropeptide secretion component HID-1 to promote pumping inhibition. PLoS Genet 10, e1004529.
• Tavares, C.D.*, Sharabi, K.*, Dominy, J.E., Lee, Y., Isasa, M., Orozco, J.M., Jedrychowski, M.P., Kamenecka, T.M., Griffin, P.R., Gygi, S.P., et al. (2016). The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1alpha Transcriptional Coactivator. J Biol Chem 291, 10635-10645.
  *equal contribution
• Sharabi, K., Lin, H., Tavares, C.D.J., Dominy, J.E., Camporez, J.P., Perry, R.J., Schilling, R., Rines, A.K., Lee, J., Hickey, M., et al. (2017). Selective Chemical Inhibition of PGC-1alpha Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell 169, 148-160 e115.
• Hatting, M., Rines, A.K., Luo, C., Tabata, M., Sharabi, K., Hall, J.A., Verdeguer, F., Trautwein, C., and Puigserver, P. (2017). Adipose Tissue CLK2 Promotes Energy Expenditure during High-Fat Diet Intermittent Fasting. Cell Metab 25, 428-437.
• Shigemura, M., Lecuona, E., Angulo, M., Dada, L.A., Edwards, M.B., Welch, L.C., Casalino-Matsuda, S.M., Sporn, P.H.S., Vadasz, I., Helenius, I.T., et al. (2019). Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans. Sci Rep 9, 18251.
• Cruces-Sande, M., Arcones, A.C., Vila-Bedmar, R., Val-Blasco, A., Sharabi, K., Diaz-Rodriguez, D., Puigserver, P., Mayor, F., Jr., and Murga, C. (2020). Autophagy mediates hepatic GRK2 degradation to facilitate glucagon-induced metabolic adaptation to fasting. FASEB J 34, 399-409.

Reviews and commentaries

• Sharabi, K., Lecuona, E., Helenius, I.T., Beitel, G.J., Sznajder, J.I., and Gruenbaum, Y. (2009b). Sensing, physiological effects and molecular response to elevated CO2 levels in eukaryotes. J Cell Mol Med 13, 4304-4318.
• Azzam, Z.S., Sharabi, K., Guetta, J., Bank, E.M., and Gruenbaum, Y. (2010). The physiological and molecular effects of elevated CO2 levels. Cell Cycle 9, 1528-1532.
• Sharabi, K., Charar, C., and Gruenbaum, Y. (2015a). Pharyngeal pumping inhibition and avoidance by acute exposure to high CO2 levels are both regulated by the BAG neurons via different molecular pathways. Worm 4, e1008898.
• Sharabi, K., Tavares, C.D., Rines, A.K., and Puigserver, P. (2015b). Molecular pathophysiology of hepatic glucose production. Mol Aspects Med46, 21-33.
• Rines, A.K., Sharabi, K., Tavares, C.D., and Puigserver, P. (2016). Targeting hepatic glucose metabolism in the treatment of type 2 diabetes. Nat Rev Drug Discov 15, 786-804.
• Hatting, M., Tavares, C.D.J., Sharabi, K., Rines, A.K., and Puigserver, P. (2018). Insulin regulation of gluconeogenesis. Ann N Y Acad Sci 1411, 21-35.
• Sharabi, K., Tavares, C.D.J., and Puigserver, P. (2019). Regulation of Hepatic Metabolism, Recent Advances, and Future Perspectives. Curr Diab Rep 19, 98.