Dr. Aharon Helman
Welcome
My lab studies how changes in the nutritional environment dictate cellular and organ adaptation, with a focus on beta cells. Specifically, we dissect the metabolic and functional heterogeneity of beta cells in sensing and responding to nutrients and how metabolic stress during aging and diabetes affects beta cell function. In addition, using human stem cell-derived beta cells we conduct high-throughput chemical and metabolic approaches to determine key regulators of human beta cell function