Diabetes, liver, glucose production, hepatocytes, nutrition, metabolism.
2001-2004 – B.Sc. in life sciences, The Hebrew University of Jerusalem. Amirim student, Graduated Cum Laude.
2005-2007 – M.Sc. in genetics. The Department of Genetics, The Hebrew University of Jerusalem. Advisor: Prof. Yosef Gruenbaum.
2007-2012 – Ph.D in genetics. The Department of Genetics, The Hebrew University of Jerusalem. Advisor: Prof. Yosef Gruenbaum.
2013 – 2019 - Postdoctoral fellowship at Dana-Farber Cancer Institute and Harvard Medical School. Host: Prof. Pere Puigserver.
Honors and Awards
2002 Winokur award from the Department of Genetics for distinguished students
2002-2004 ‘Amirim,’ special program for outstanding students in life sciences
2008 The Israel and Edith Pollack award for excellence in research and academic achievements
2010 Katzir-Katchalsky Student Travel Fellowship
2017 Keystone Symposia Travel Scholarship
2005-2012 - Teaching Assistant at The Department of Genetics, The Hebrew University of Jerusalem.
Participation in Scientific Conferences
Selected for oral presentation at Keystone Symposia conference – Diabetes (2017).
American Heart Association Postdoctoral Fellowship 01/01/2015 - 12/31/2016
Kfir Sharabi (PI)
Methionine as a Signaling Molecule that Affects PGC-1alpha Acetylation and Gluconeogenesis
The objective of this study was to identify the mechanisms whereby availability of the essential amino acid methionine controls hepatic PGC-1aacetylation and to evaluate what effects this phenomenon has on hepatic glucose production in vivo.
Charles A. King Trust Postdoctoral Research Fellowship 09/01/2017 – 08/31/2019
Kfir Sharabi (PI)
Dissecting mechanisms that control hepatic glucose production using a newly identified anti-diabetic drug
The major objective of this proposal is to identify and characterize the cellular events whereby compound SR-18292 regulates hepatic glucose production through inactivation of the PGC-1αtranscriptional complex.
“Selective Inhibition of Gluconeogenic Activity”. DFS-18160 provisional application.