Table of Contents

Contact Us

Head of Institute: Prof. Oren Tirosh

Administrative manager: Rakefet Kalev

Office Address:
Institute of Biochemistry, Food Science and Nutrition,
Robert H. Smith Faculty of Agriculture, Food and Environment,
The Hebrew University of Jerusalem, 
Herzl 229, Rehovot 7610001, ISRAEL

Tel: +972 - (0)8-9489385
Fax: +972 - (0)8-9363208
Email Address:

List of Publications

1. Reifen R, Gale R, Kerem E, Armon Y, Brand A, Dagan J, Kohn G 1986 Partial detection of the short arm of chromosome 3, further delineation of the 3p25-3ptr syndrome. Clin Genetics 29, 117-120 (2.395, 40/113, 15).

2. Korman SH, Leblanc SM, Spira DT, Elon Y, Reifen R, Deckelbaum RJ1986. Giardia lamblia identification of strains in man. Para Res 72, 173-180 (1.025; 11/21, 46).

3. Armon Y, Steinberg A, Appelbaum A, Brand A, Reifen R, Gale R 1986 Hypoplastic left heart syndrome in the newborn; physiological, surgical and ethical aspects. Harefuah 112, 538-541.

4. Brand A, Reifen R, Armon Y, Kerem E, Horenstein E, Gale R 1987 Double mitral valve complete atrioventricular canal and tricuspid atresia in chromosome p-syndrome. Pediatr Cardiol 8, 55-57 (0.720; 41/69,1).

5. Klar A, Corcos AP, Gross-Kieselstein E, Reifen R, Navon P, Branski D. 1987. Near normalization of metabolic abnormalities by prolonged infusion in a girl with congenital lipodystrophy. Diabetes Care 10, 257-258 (5.4; 16/81, 4).

6. Kerem E, Urbach Y, Reifen R, Ish-Hurvitz M, Abramov A, Branski D.1987 Transient hyperphosphatasemia of infancy. J Child Neurol 22, 890-892 (1.393; 22/69, 2).

7. Steinberg A, Reifen R, Leifer M. 1987. Efficacy of valporic acid in the treatment of Sydenham chorea. J Child Neurol 2, 233-234 (1.393; 22/69, 5)

8. Brand A, Kerem E, Reifen R, Keren A, Branski D. 1988. Myocardial damage following scorpion bite: echocardiograph follow-up. Pediatr Cardiol 9, 59-63 (0.720; 41/69,11).

9. Klar A, Reifen R, Vinograd I, Dudai M, Branski D 1988 Acute hydrops of the gallbladder in a child. Ped Surg 4, 285-287 (0.99; 19/53,4).

10. Sadovsky E, Reifen E, Reifen R, Ohel G.1988. Abnormal antepartum fetal heart rate in high risk pregnancies with good outcome. Asia Oceania J Obstet Gynecol 14, 267-273.

11. Hurvitz H, Barash V, Elpeleg O, Kerem E, Reifen R, Mor C, Branski D. 1989. Glycogen storage disease, Fanconi syndrome, abnormal galactose metabolism and mitochondrial myopathy. Eur J Ped 149, 48-51 (1.220; 24/69, 7).

12. Lysi Y, Werzberfger A, Gavish A, Reifen R, Liberson A, Dudai M.1989. Intrapleural installation of streptokinase in the treatment of organizing empyema. Isr J Med Sci 25, 284-287 (0.5; 53/100, 10).

13. Brand A, Kerem A, Reifen R, Gross-Kieselstein E, Amir N.1989. Echocardiography and Doppler findings in the Williams syndrome. Am J Cardiol 1:63, 633-635 (2.637; 11/53, 8).

14. Reifen R, Nadgari M, Hurvitz H, Barash V, Gutman A.1989. Hepatomegaly in utero in glycogenesis 3. Acta Pediatr Scan 78, 945-955 (1.582; 18/69, 2).

15. Kiderman A, Branski D, Mor Y, Reifen R, Navon P, Abramov A. 1989. Acute urinary retention in childhood: Therapeutic approaches. Ped Rev Commun 3, 303-308.

16. Dolberg S, Hurvitz H, Reifen R, Sternberg A, Navon P, Branski D.1990. Seizures in the course of hepatitis A. Am J Dis Child 144, 130-141 (1.49;8/61 1).

17. Khoshoo V, Reifen R, Gold BD, Sherman PM, Pencharz PB.1991. Nutritional manipulations in the management of Dumping syndrome. Arch Dis Child 66, 1447-1448. (2.12; 9/69, 14).

18. Flechner I, Aronof G, Reifen R, Landau H.1992. Detection of albumin binding abnormalities in the sera of patients with familial dysalbuminemic hyperthyroxinemia using isoelectric focusing. J Clin Endocrinol Metab 18, 229-240 (5.16; 10/90 2).

19. Gold DB, Bhopalam PS, Reifen RM, Harvey E, Marcon MA. 1992. Gastrointestinal manifestations of gastrocystoplasy in children. Arch Dis Child 67, 1272-1276 (2.12; 9/69, 17).

20. Reifen R, Cutz E, Griffith A, Ngan B, Sherman PM. 1994. Tufting enteropathy: a newly recognized disease entity associated with intractable diarrhea of infancy. J Ped Gastro Nutr 18, 373-385 (2.077; 10/69, 44).

21.Reifen RM, Sherman PM. 1994. Intestinal lympangiectasia secondary toneuroblastoma. CanJ Gastroenterol8, 49-61 (0.3; 34/42 58).

22. Reifen R, Rosooli I, Drumm B, Murphy K, Sherman P. 1994. Helicobacter pylori infection in children: Is there specific symptomatology? Dig Dis .Sci 39, 1488-1491 (1.87; 10/42, 46).

23. Khoshoo V, Zembo M, King A, Dhar M, Reifen R, Pencharz P.1996. Incidence of gastroesophaegeal reflux with whey and casein-based formula in children with severe neurological impairment. J Ped Gastroenterol Nut 22, 48-55 (2.077; 10/69, 9).

24. Reifen R, Ashkenazy A, Nyska A. 1996. Use of an in vitro Sabra rat model for the screening of potential agents involved in Celiac disease. Cell Vision 3, 86-89.

25. Khoshoo V, Reifen R, Neuman M, Griffith A, Pencharz P.1996. Effect of low- and high-fat peptide-based diets on body composition and disease activity in adolescents with active Crohn’s disease. J Parent Ent Nutr 20, 401-405 (1.928; 17/50, 29).

26. Reifen R, Altman Y, Zadik Z.1996. Vitamin A levels and growth hormone axis. Horm Res 46, 279-281 (1.22; 61/90, 2).

27. Gilmour S, Hershkop M, Reifen R , Gilday D, Roberts EA.. 1997 Outcome of hepatobiliary scanning in neonatal hepatitis syndrome. J Nucl Med 38, 1279-1282(4.510; 5/72, 36).

28. Zusman I, Reifen R, Lvni O, Smirnoff P, Gurevich P, ,Koroll D, Sandler B, Nyska A,Tendler Y, Madar Z 1997. Role of apoptosis proliferative cell nuclear antigen and p53 protein in the tumor-preventive effect of the high-mushroom-diet on chemically induced colon cancer in rats. Anti-Cancer Research 17, 1-9.(1.456; 59/101, 32).

29. Reifen R, Lerner A, Buskila D.1997. Prolactin in celiac disease: a marker ofdisease activity. Arch Dis Child 77, 155-157 (2.12; 9/69, 8).

30. Rahlenbeck SI, Yohannes G, Molla K, Reifen R, Assefa A. 1997. Infection with HIV, syphilis and hepatitis B in Ethiopia: A survey in blood donors.Int J STD AIDS 8, 261-264 (1.43; 25/34, 22).

31. Reifen R, Agami O, Biesalski H, Weiser H, Naim M. 1998. Impaired sweet-taste responses in vitamin-A deficient rats. Metabolism 47, 1-3 (1.65; 43/83, 7).

32. ZadikZ, Frishberg Y,Drukker YA, Blachar Y, Lotan D, Levy S, Reifen R. 1998. The effect of nutrition on growth in children with end-stage renal disease during and before growth hormone therapy. Metabolism 47, 264-268 (1.65; 43/83, 10).

33. Reifen R,Nyska A, Koperstein L,Zusman I.1998. Intestinal and hepatic kinetics and mucinic changes in vitamin A deficiency. Int J Mol Med 1, 579-582 (1.689, 40/83 8).

34. Reifen R, Blank M, Afek A, Sklan D, Kopelovic M, Gershwin E, Shoenfeld Y.1998. Dietary PUFA decrease anti ds-DNA and anticardiolipin ab in a mouse model of systemic lupus erythematosus. Lupus 7, 192-197 (1.875, 56/114, 18).

35. Reifen R, Reif S, Buskila D, Berkovitz Z, Lerner A.1998. Transthyretin is a reliable marker of celiac disease activity. J Med. 29, 30-36 (0.21; 83/160, 2).

36. Reifen R, Edris M, Nussinovitch A.1998. Fortification of an edible sponge as an intervention model to treat children with vitamin A deficiency. J Hydrocolloids 12, 111-114 (1.357; 13/90, 12).

37. Reifen R, Zaiger G, Uni Z.1998. Effect of vitamin A deficiency on small intestinal brush border enzymes in a rat model. Int J Vitaminol Res 68, 281-286 (0.949; 25/50, 15).

38. Uni Z, Zaiger G, Reifen R.1998. Vitamin A deficiency induces morphometric changes and decreased functionality in chicken small intestine. Br J Nutr 80,401-407 (1.713 ; 12/50, 21).

39. Scheppach W,Bingham S, Boutron-Ruault MC, de Verdier MG, (c), Moreno V,Reifen R, Riboli E, Seitz HK, Wahrendorf J.1999. WHO consensus statement on the role of nutrition in colorectal cancer. E J Cancer Prev 8, 57-62 (1.938, 41/107, 55).

40. Biesalski HK, Frank J, Beck SC, Heinrich F,Illek B, Reifen R, Gollnick H,Seeliger M , Wissinger B, Zrenner E. 1999. Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein. Am J Clin Nut 69, 931-936 (3.958, 3/50, 45).

41. Reifen R, Khoshoo V, Dinari G. 1999. Effect of parenteral nutrition on oral intake. J Pediatr Endocrinol Metab 12, 203-205 (0.6, 45/72, 1).

42. Zadik Z, Amer R, Dolfin Z, Arnon S, Cohen D, Mogilner B, Reifen R. 1999. Urinary free cortisol (UFC) values in newborns under stress. J Ped Endocrinol Metab 12, 543-547 (0.6, 45/72, 8).

43.Biesalski H,Reifen R, Furst P,Edris M. 1999. Retinyl palmitate supplementation by inhalation of an aerosol improves vitamin A status of preschool children in Gondar (Ethiopia) Br J Nut 82, 179-182 (1.94, 11/50, 6)

2000-2005   |   ^

44. Reifen R, Matas Z,Berkovitch Z, Bujanover Y.2000. Iron supplementation may aggravate the inflammatory process in colitis induced in rats. Dig Dis Sci 45, 394-397 (1.49 26/45, 38).

45. Levine A,Bujanover Y,Gass S, Reifen R, Lehman D,Reif S 2000. Comparison of assays for anti-endomysial and anti-transglutaminase antibodies fordiagnosis of celiac disease. Israel Med Assoc J 2, 122-125 (0.66, 81/133, 13).

46. Reifen R, AmitalH,Blank M, Sklan D,Berkovitch Z, Gershwin E,Shoenfeld Y. 2000 Linseed oil suppresses the anti-beta-2-glycoprotein in experimental antiphospholipid syndrome. J Autoimmunity 15, 381-385 (2.17, 51/116, 3).

47. Uni Z, Zaiger G, Gal Garber O, Pines M, Rozenboim I, Reifen R.2000. Vitamin-A deficiency interferes with proliferation and maturation of cells in the chicken small intestine. Brit Poultry Sci 41, 424-429 (0.705, 17/44,18).

48. Abbo S, Grusak M, Tzuk T , Reifen R. 2000. The relationship between seed size and calcium content of chickpeas seed. Plant Breeding 119, 1-6. (0.77, 18/57, 13).

49. Wardi Y, Reifen R, Hussein I, Bruk R. 2001. Beta carotene attenuates experimentally induced liver cirrhosis in rats. Israel Med Assoc J3, 151-154 (0.6, 45/107 7).

50. Zadik Z, Wittenberg I, Segal N, Altman Y, Zung A,Reifen R. 2001. Reduction of fat mass and leptin levels in growth hormone treated children. Int J Obesity 25, 538-542 (2.196, 12/50, 3).

51. Reifen R , Nur T, Matas Z,Halpern Z.2001. Lycopene supplementaion attenuates the inflammatory status of colitis in a rat model. Int J Vitaminol Research 71, 347-352. (1.175, 25/50, 16).

52. Dalal I, Benson I, Reifen R,Amitai Z,Shohat T,Rahmani S,Levine A,Balin A,Somech E.2002. Food allergy is a matter of geography after all: Sesame as a major cause of severe IgE mediated food allergic reactions among infants and young children in Israel. Allergy 57, 362-365. (3.66, 3/15, 107).

53. Shoseyov D, Bibi H,Biesalski H,Reifen R. 2002. Repeated allergen challenge in rats increases vitamin A consumption. Chest 122, 1407-1411 (2.96, 6/30 6).

54. Khoshoo V, Reifen R. 2002. Use of energy-dense formulae for treating infants with non-organic failure to thrive. Eur J Clin Nut 56, 921-924 (1.94, 18/50 2).

55. Crawford M, Galli C, Simopolus A,Reifen R. 2002. Social and economic capital and the inequality of international public health.Lancet 359, 258-259 (15.39, 3/107,1).

56. Bruk R, Aeed H , Schey R,Matas Z, Reifen R, Zaiger G, Hochman A,Avni Y. 2002.Pyrolidinedithiocarbamate protects against thioacetamide fulminant hepatic failure in rats. J Hepatol 36, 370-377. (4.97, 5/45, 52).

57. Nur T, Peijnenburg A, Noteborn H,Baykus H, Reifen R. 2002. Similar gene expression patterns in vitamin A deficiency and chemically induced colitis in rats as revealed by DNA microarray technology. J Nutr 132, 2131-6. (3.620, 4/50, 8).

58. Livny O, Kaplan I, Reifen R, Polac-Charcon S, Madar Z, Schwartz B. 2002. Lycopene inhibits proliferation and enhances gap- communication of KB-1 human oral tumor cells. J Nutr 132, 3754-3759. (3.620, 4/50, 68).

59. Reifen R, Nur T, Ghebermeskel K, Zaiger G,Uritsky R, Pines P. 2002. Vitamin A deficiency exacerbates inflammation in a rat model of colitis through activation of NF-kappa B and collagen formation. J Nutr 132, 2743-2747 (3.620, 4/50,28).

60. Reifen R, Haftel L, Manor G, Sklan D, Edris M,Khoshoo V, GhebremeskelK. 2003. Ethiopian-born and native Israeli school children have different growth patterns. Nutrition 19, 427-431 (2.32, 11/53 2).

61. Kori M , Gladish V, SokolovskiaN, Huszar M,Beer Gabel M,Reifen R. 2003. The significance of routine duodenal biopsies in pediatric patients undergoing upper intestinal endoscopy. J Clin Gastroenterol37, 39-41 (1.56 26/47, 14).

62. Dalal I, Binson I, Levine A,Somekh E,Balin A, Reifen R. 2003. The pattern of sesame sensitivity among infants and children. JPed All. Immunol 14, 312-316 (1.57, 6/15, 28).

63. Livny O, Reifen R,Levy I,Madar Z,Faulks R,Southon S, Schwartz B. 2003. Beta carotene bioavailability from differently processed carrot meals in human ileostomy volunteers. Eur J Nutr42, 338-345. (1.864 19/53, 31).

64. Reifen R, Haftel L,Faulks R, Southon S, Kaplan I,Schwartz B(c) 2003. Plasma and buccal mucosal cell response to short term supplementation with all trans-β-carotene and lycopene in human volunteers. Int JMol Med12, 989-93 (1.94 40/83.3).

65. Zadik Z , Borondukov E, ReifenR. 2003. Adult height and weight of breast fed Israeli infants. J Ped GI Nutr;37(4):462-7. (1.402, 25/68, 7).

66. Livny O,Kaplan I,Reifen R,Polak-Charcon S,Madar Z,Schwartz B. 2003. Oral cancer cells differ from normal oral epithelial cells in tissue-like organization and in response to lycopene treatment: an organotypic cell culture study. Nutr Cancer 47(2):195-209.(1.972 18/53, 8).

67. Zadik Z, Sinai T, Zung A, Reifen R. 2004 Vitamin A and iron supplementation is as efficient as hormonal therapy in constitutionally delayed children. Clinical Endocrinology 60,682–687 (3.02, 30/87, 6).

68. Reifen R, Nissenkorn A, Matas Z Bujanover Y. 2004 5-ASA and lycopene decrease the oxidative stress and inflammation induced by iron in rats with colitis. J Gastroenterol 39:514-519. (1.20 33/46, 28).

69. Reifen R, Mor A, Nyska A.2004. Vitamin A deficiency aggravated rotavirusinfection in CD-1 mice through extensive involvement of the gut.Int J VitamNutrRes 74: 355-361 (1.175; 22/50, 4).

70. Zaiger G ,NurT , Berkovich Z, Barshak I, Goldberg I , Reifen R. 2004. Vitamin A exerts its activity at the transcriptional level in the small intestine. Eur J Clin Nutr; 43:259-66(2.13 16/53, 10).

71. Uritski R, Barschak I, Bilkis I, Ghebremeskel K, Reifen R. 2004, Dietary ironaffects inflammatory status in a rat model of colitis. J Nutr 134: 134: 2251-2255 (3.24, 7/53,11).

72. Zhou D,Zaiger G ,Ghebremeskel K, Crawford M A,Reifen R. 2004.Vitamin A deficiency r educes liver and colon docosahexaenoic acid levels in rats fed high linoleic and low alpha-linolenic acid diet..Prostaglandins Leukot Essent Fatty Acids 71(6):383-9. (1.74 2/2, 6) .

73. Wolff N, Yannai S, Karin N, Levy Y, Reifen R, Dalal I, Cogan U. 2004. Identification and characterization of linear B-cell epitopes of beta-globulin, a major allergen of sesame seeds. J Allergy Clin Immunol;114(5):1151-8. (.7,25 1/15, 9).

74. Zadik Z pi, Borondukov Ec ,Sinai T s, Zung Ac , Yaniv Ic Reifen Rpi. 2005 Longitudinal monitoring of bone accretion measured by quantitative multi-site ultrasound (QUS) of bones in patients with delayed puberty (a pilot study. Osteoporosis Int.416(9):1036-41; (4.216 22/89 4).

75. Zadik Z pi, Sinai T s, Zung Ac , Reifen Rpi. 2005. Longitudinal Monitoring of Bone Measured by Quantitative Multisite Ultrasound in Patients With Crohn's Disease. J Clin Gastroenterol. ;39(2):120-123. (2.25 19/46 2)

76. Abbo S pi , Molina Cc,. Jungmann, Rc.. Grusak, M. Ac. Berkovitch Z t, Reifen Rs,Kahl G c, Winter Pc and Reifen R pi2005 Quantitative trait loci governing carotenoid concentration and weight in seeds of chickpea (Cicer arietinumL.) Theoretical and Applied Genetics: (3.06 1/48 ,38)

77. Zadik Z pi Sinai Ts, Zung Ac, Reifen R pi 2005 Effect of Nutrition on growth in short stature before and during growth hormone therapy. Pediatrics116;68-72 (4.27 1/73,).

2006-2009   |   ^

78. Aharoni-Simon Ms,Reifen R pi, Tirosh O pi. 2006 ROS-Production-Mediated Activation of AP-1 but Not NFκB Inhibits Glutamate-Induced HT4 Neuronal Cell Death. Free Radic Biol Med. (5.44 43/276, 3).

79. Zhou Ds, Ghebremeskel Kc, Crawford Mc, Reifen R pi Vitamin A deficiency enhances docosahexaenoic and osbond acids in liver of rats fed an alpha linolenic acid-adequate diet. Lipids. 2006 Mar;41(3):213-9(1.935; 24/55, 5).


80. Amit Romach Es,Reifen R pi , Uni Z pi. 2006, Mucosal function in rat jejunum and ileum is altered by induction of colitis. Int J MolMed 18:721-7. (1.85 48/82 11).


81.Karu N, sReifen R, pi Kerem Z pi. 2007 Weight gainreduction in mice fedpanax ginsengsaponin, a pancreatic lipase inhibitor, Journal of Agriculturaland Food Chemistry 18;55(8):2824-8. (3.17 7/103 31).

82. Tirosh O pi, Levy Es, Reifen R pi, 2007 High-Selenium Diet Protects Against TNBS-induced Acute Inflammation, Mitochondrial Dysfunction and Secondary Necrosis in Rat Colon ,Nutrition;23:878-86. (2.10 21/56 12).

83. Stark A pi, Weiss Ns, Chapnik Lc, Reifen R pi. 2008, Dietary intake in Pilots of the Israeli Air Force, Military Medicine 173(8):780-4 (0.640 83/107).

84. Amit-Romach Es, Uni Z pi and Reifen R pi (2008) Therapeutic potential of two probiotics in inflammatory bowel disease as observed in the TNBS model of colitis. Dis Colon Rectum 51(12):1828-36(3.24 24/55 10).

85. Amit Romach Es, Uni Z pi,Cheled Ss, Berkovich Zt, Reifen R pi 2008Bacterial population and innate immunityrelated genes in rat gastroitnerstinaltract are alteredby a vitamin A deficient diet. Journal Nutritional Biochemistry, 20(1):70-7 (4.352, 4/59.5).

86. Shamir M pi, Shilo Yc, Friedman Ac, Chai Oc,Reifen Rc, and Miarac L.2008 Sub occipitalcraniectomy in a Lion (Panthera leo)with occipitalbone malformation and hypovitaminosis A, J of Zoo and Wild Life Medicine, 39(3):455-9. (0.386 98/135, 2).

2010-   |   ^

87. Lubetzki Rs Mimouni FB pi, Dolberg Sc,Reifen R pi,Ashbel Gc,Mandel Dc. 2010 2010. The effect of musicby Mozart on energyexpenditure in growing preterminfants. Pediatrics, 125(1):24-8 (4.68 3/94 3)

88. Amit Romach Es, Uni Z pi, Reifen R pi. 2010. Multistep Mechanism of Probiotic bacterium, the Effect on Innate Immune System", Molecular Nutrition & Food Research, 54(2):277-84. (4.35 1/118, 8)

89. R Gross-Tsubery Rs,Chai Oc, Shilo Yc,Miara Lc, Horowitz Ic,Shmueli A c, Itzhak Aizenberg I c, Hoffman C c, Reifen R c and Shamir M pi 2010. Computed tomography analysis of skull malformation related to vitamin A deficiency in lions (Panthera leo) Veterinary Radiology & Ultrasound,. 51(1):34–38. (1.055 52/142).

90. Weiss B pi, Barshak I c Onaca N c Godberg I c Berkovich Zt,Meltzer E c,Yonas A c,Reifen R pi,. 2010. Vitamin A Deficiency Associated with Enhanced Proliferation of Bile Duct Epithelial Cells in the Rat. IMAJ, l2:78-82. (0.89, 81/133 1).

91.Brand As, Hallot As Bauer Ns, Ghebremeskel K c, Reifen R pi, Richter-Landsberg C pi 2010.Membrane lipid modification by polyunsaturated fatty acids sensitizes olgodendroglial OLN-93 cells against oxidative stress and promotes upregulation of heme oxygenase-1(HSP32). Journal of Neurochemistry, 113(2):465-476. (3.99, 40/221, 4).

92. Abbo Shahal pi , BonfilD c ,Kerem Z , Berkovich Zt , Reifen R pi 2010.Towards enhancing lutein concentration in chickpea, cultivar and management effects" Plant Breeding. 129: 407-411 (1,02, 72/155 ).

93. Zadik Z pi,Sinai Ts, Zung A c, Reifen R pi. 2010. Functional Food for Acceleration of Growth in Short Children BornSmall fro Gestational Age. J Pediatr Endocrinol Metab. 23:5:435-441 (0.738, 78/94, 2)

94. Dadon Barel S s Shahar R c,Katalan V sMonsenego c E, Reifen R pi.2011Leptin administration affects growth and skeletal development in a rat IUGR model-preliminary study. Nutrition, 27(9):973-7. (2.604 23/66 1)

95. Regev-Tobiass H, Reifenpi, R. Endeveltc R, Havkinc C, Cohenc E, Sternc ,A.H. Stark pi.2012. Dietary Acculturation and Increasing Rates of Obesity in Ethiopian Women Living in Israel. Nutrition;28(1):30-4. (2.604 23/66).11