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Head of Institute: Prof. Oren Tirosh

Administrative manager: Rakefet Kalev

Office Address:
Institute of Biochemistry, Food Science and Nutrition,
Robert H. Smith Faculty of Agriculture, Food and Environment,
The Hebrew University of Jerusalem, 
Herzl 229, Rehovot 7610001, ISRAEL

Tel: +972 - (0)8-9489385
Fax: +972 - (0)8-9363208
Email Address: rakefetk@savion.huji.ac.il

IRG project: Freeze Control in Food by Ice Binding Proteins

Marie Curie Reintegration Grants abstract: 
The freezing processes play a main role in food science. The storage of food in a frozen form has become one of the most common ways to elongate the shelf-time of many food products. Nevertheless, during freezing and thawing, cell walls can be ruptured by the ice crystals or can be separated by extra-cellular ice growth during the recrystalization process. Ice binding proteins (IBP), which include antifreeze proteins, ice nucleating proteins, and recrystalization inhibitors, hold great promise for improvements in food supply and quality through the prevention of frost damage to crops and the enhancement of preservation technology. The interaction of IBPs with ice crystals suggests that these proteins can be use as a means of controlling ice in food in each level of its production and processing. I propose to investigate freeze control in food by ice binding proteins. My background includes a PhD in ice physics and in particular optical investigation of crystal growth, a post-doctorate work in biophysics and biotechnology and academic position in Ohio University in where I investigate IBPs. In my post-doctorate work at Caltech, I developed instrumentation that was the basis for the biotechnology company Helicos Bioscience, which led to the development of the first instrumentation that can sequence DNA at the single molecule level. In the past few years at Ohio University, I have combined the subjects of ice physics and biophysics and have developed methods for investigating antifreeze proteins in novel ways. I have developed unique instrumentation to assess the activity of the proteins, in particular microfluidics and fluorescence microscopy. At the Hebrew University Faculty of Agriculture, Food and Environment I intend to establish a Food Biophysics lab in which I will continue my basic research on the mechanism of freeze control and investigate the potential of IBPs to improve the quality of different food materials upon cooling, freezing and thawing.