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AnchorDock for Blind Flexible Docking of Peptides to Proteins

Citation:

Slutzki, M. ; Ben-Shimon, A. ; Niv, M. Y. . Anchordock For Blind Flexible Docking Of Peptides To Proteins. In Modeling Peptide-Protein Interactions: Methods and Protocols; Schueler-Furman, O. ; London, N., Eds.; Springer New York: New York, NY, 2017; pp. 95–108.

Abstract:

Due to increasing interest in peptides as signaling modulators and drug candidates, several methods for peptide docking to their target proteins are under active development. The ``blind'' docking problem, where the peptide-binding site on the protein surface is unknown, presents one of the current challenges in the field. AnchorDock protocol was developed by Ben-Shimon and Niv to address this challenge.

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