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Immobilized random peptide mixtures exhibit broad antimicrobial activity with high selectivity | Biochemistry, Food Science and Nutrition

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Immobilized random peptide mixtures exhibit broad antimicrobial activity with high selectivity

Citation:

Cheriker, H. ; Stern Bauer, T. ; Oren, Y. ; Nir, S. ; Hayouka, Z. . Immobilized Random Peptide Mixtures Exhibit Broad Antimicrobial Activity With High Selectivity. CHEMICAL COMMUNICATIONS 2020, 56, 11022-11025.

Date Published:

SEP 25

Abstract:

In the current study, we evaluated the antimicrobial activity of randomly-sequenced peptide mixtures (RPMs) bearing hydrophobic and cationic residues thatwere immobilized on beads. We showed that these beads exhibit high and broad bactericidal activity against various pathogenic bacteria while possessing minimal hemolytic activity.